Secondary Fisher–Evans syndrome in a child with activated PI(3)kd syndrome and lymphoma

Evans syndrome, a combination of autoimmune hemolytic anemia and immune thrombocytopenia, is rare disease in children. In childhood, it may turn out to be one the first manifestations primary immunodeficiency or an dysregulation syndrome. Here we present clinical case patient who was initially diagnosed with syndrome did not respond well therapy. Based on results genetic testing, child then immunodeficiency, namely, activated PI(3)kd During follow-up, developed lymphoma had undergo radical treatment (allogeneic hematopoietic stem cell transplantation). The patient's parents gave consent use their child's data, including photographs, for research purposes publications.